Avidya, spiritual ignorance, is the source of all the other obstacles: arrogance, desire, aversion and thirst to survive.

Verse 2.3

अविद्याअस्मितारागद्वेषाभिनिवेशः क्लेशाः ॥३॥

avidyā-asmitā-rāga-dveṣa-abhiniveśaḥ kleśāḥ ॥3॥

Ignorance, egoism, attachment, aversion and clinging to life - are the five Klesas ( Obstacles)

Verse 2.4

अविद्या क्षेत्रमुत्तरेषाम् प्रसुप्ततनुविच्छिन्नोदाराणाम् ॥४॥

avidyā kṣetram-uttareṣām prasupta-tanu-vicchinn-odārāṇām ॥4॥

A lack of Knowledge (avidya) is the source of most kleshas (obstacles) and can be latent, incipient, full fledged or overwhelming. ||4||

Suffering are of three levels, intellectual, emotional and instinctive.

 Avidya belong to the field of intelligence; here lack of spiritual knowledge combined with pride or arrogance inflates the ego, causing conceit and the loss of one's sense of balance.

Raga and dvesha belong to emotions and feelings. 

Raga is desire and attachment, Dvesha is hatred and aversion. 

Succumbing to excessive desires and attachments or allowing oneself to be carried away by expressions of hatred, creates disharmony between body and mind, which may lead to pain. 

Abhinivesa is instinctive:

Concern for one's own survival.

Clinging to life makes one suspicious in dealings with others, and causes one to become selfish and self-centred.

The root causes of these five suffering are the functions and thoughts of the mind.

The 'I' thought arises from the mind which is the root of all the cause of the pain and suffering.

Avidya, spiritual ignorance, is the source of all the other obstacles: arrogance, desire, aversion and thirst to survive. 

These suffering whether dormant, thin, or fully active, are obstacles to enlightenment. 

Patanjali classify avidya as the "breeding-ground" of all Suffering, whatever its nature.

PATANJALI YOGA SUTRAS